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In this photo dated Tuesday, Nov, 29, 2016 the Soyuz-FG rocket booster with the Progress MS-04 cargo ship is installed on a launch pad in Baikonur, Kazakhstan. The unmanned Russian cargo space ship Progress MS-04 broke up in the atmosphere over Siberia on Thursday Dec. 1, 2016, just minutes after the launch en route to the International Space Station due to an unspecified malfunction, the Russian space agency said.(Oleg Urusov/ Roscosmos Space Agency Press Service photo via AP)

MOSCOW (AP) — An unmanned Russian cargo spaceship heading to the International Space Station broke up in the atmosphere over Siberia on Thursday due to an unspecified malfunction, the Russian space agency said.

The Progress MS-04 cargo craft broke up at an altitude of 190 kilometers (118 miles) over the remote Russian Tuva region in Siberia that borders Mongolia, Roscosmos said in a statement. It said most of spaceship's debris burnt up as it entered the atmosphere but some fell to Earth over what it called an uninhabited area.

Local people reported seeing a flash of light and hearing a loud thud west of the regional capital of Kyzyl, more than 3,600 kilometers (2,200 miles) east of Moscow, the Tuva government was quoted as saying late Thursday by the Interfax news agency.

The Progress cargo ship had lifted off as scheduled at 8:51 p.m. (1451 GMT) from Russia's space launch complex in Baikonur, Kazakhstan, to deliver 2.5 metric tons of fuel, water, food and other supplies. It was set to dock with the space station on Saturday.

Roscosmos said the craft was operating normally before it stopped transmitting data 6 ½ minutes after the launch. The Russian space agency would not immediately describe the malfunction, saying its experts were looking into it.

This is the third botched launch of a Russian spacecraft in two years. A Progress cargo ship plunged into the Pacific Ocean in May 2015, and a Proton-M rocket carrying an advanced satellite broke up in the atmosphere in May 2014.

But both Roscosmos and NASA said the crash of the ship would have no impact on the operations of the orbiting space lab that is currently home to a six-member crew, including three cosmonauts from Russia, two NASA astronauts and one from the European Union.

Orbital ATK, NASA's other shipper, successfully sent up supplies to the space station in October, and a Japanese cargo spaceship is scheduled to launch a full load in mid-December.

NASA supplier SpaceX, meanwhile, has been grounded since a rocket explosion in September on the launch pad at Cape Canaveral, Florida. The company hopes to resume launches in December to deliver communication satellites.

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This version corrects the spelling of the region to Tuva, not Tyva.

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Aerospace Writer Marcia Dunn in Cape Canaveral, Florida, and Vladimir Isachenkov in Moscow contributed to this report.